Pinnacle Medicine & Medical Sciences

(ISSN: 2360-9516)

May 2017, Vol. 4 (2).

© Author(s) 2017. This work is distributed under the Creative Commons Attribution 3.0 License.

Research Article


Association Of The Hipoadiponectinemia With Smoking And Its Effects On The Body: A Systematic Review

Alexander Oswaldo Ojeda Crespo Md-Mgs1*, Alexander Xavier Ojeda Cedillo Md2, Peter Oswaldo Ojeda Cedillo Md3, Mercedes Elizabeth Sánchez López Md4, Andrés Eduardo Ojeda Cedillo Md5

Teacher - Researcher,1*
Technical University of Machala, Ecuador.

Institute of Social Security, Ecuador.

Accepted 2 May, 2017; Available Online 3 May, 2017.


Objective: To evaluate the relationship between smoking and hypoadiponectinemia and the effects it causes in humans. Methods: A systematic review was conducted in PubMed, Cochrame, EMBASE, Plos, BMC Public Health and American Thoracic Society, 20 studies selected, applying criteria of inclusion and exclusion respectively, according to the interests of the investigation. It was analyzed in a global population of 1'070.425 cases. Results: Low levels of adiponectin in people exposed to snuff were associated with increased risk of diabetes, nonalcoholic hepatic steatosis (NASH), early atherosclerosis, renal cell carcinoma and asthma (95% CI P = 0.04). It was determined that hypoadiponectinemia during pregnancy was associated with intrauterine disorders in newborn baby (95% CI P = 0.057). The findings suggest that exposure to snuff dipping has a stronger association with low levels of adiponectin, high glucose and triglycerides (95% CI P = 0.001); and that adiponectin is considered a predictive factor in the activity and prognosis of chronic diseases such as rheumatoid arthritis. Conclusion: The findings of this study suggest that decreased serum adiponectin levels represent a significant relevant factor in humans, mainly in which they are immersed or exposed to smoking; causing such effects that lead people to be susceptible to cardiometabolic diseases, cancer or other comorbidities.

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